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Research Paper | Medicine Science | Iraq | Volume 5 Issue 2, February 2016
The Role of Reproductive Hormones on Fertility with Beta-Thalassemia
Muhammad O. Al-Muhammadi | Bushra J. Al-Rubaie | Mais A. Al-Turaihi
Abstract: thalassemia major is a common genetic blood disorder which is the most severe form of thalassemia, and an inherited disease resulting from homozygosity or compound heterozygosity for beta thalassemia with severe reduction or total absence of beta globin chains. Blood transfusions are mandatory for survival of beta thalassemia major patients which leads to iron overload, subsequent tissue damage and oxidative stress. Failure of pubertal growth, delay or absence of sexual development, amenorrhea, sexual dysfunction and infertility due to hypogonadism are well-recognized disturbances of the hypothalamic pituitary gonadal axis in -thal patients.
Keywords: Beta thalassemia major, serum iron, reproductive hormones
Edition: Volume 5 Issue 2, February 2016,
Pages: 78 - 82
Similar Articles with Keyword 'Beta'
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Case Studies, Medicine Science, India, Volume 3 Issue 8, August 2014
Pages: 1569 - 1571A Case Study of Drug Induced Acute Interstitial Nephritis with combined use of Beta-Lactams, NSAIDs and Amikacin
Rohith Vanam | P. Mounika Reddy
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Research Paper, Medicine Science, India, Volume 4 Issue 6, June 2015
Pages: 1183 - 1186Prevalence of ESBL and MBL in Acinetobacter Species Isolated from Clinical Samples in Tertiary Care Hospital
Molay Banerjee | B.L. Chaudhary | Snehanshu Shukla