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Research Paper | Medicine Science | Ethiopia | Volume 3 Issue 5, May 2014 | Rating: 6.6 / 10
Survival Analysis of HIV Infected People on Antiretroviral Therapy at Mizan-Aman General Hospital; Southwest Ethiopia
Tezera Moshago | Demissew Berihun Haile | Fikire Enkusilasie
Abstract: Provision of intervention with antiretroviral therapy has significantly changed the course of the AIDS epidemic form to less life-threatening chronic disease. Thus; the study was aimed at assessing the survival and risk factors of death in people living with HIV/AIDS after initiation of antiretroviral therapy at the Hospital. A retrospective cohort study design was applied in this study. The cohort was stratified into three age groups: children; adolescents; and adults. Kaplan-Meier method was effectively run to estimate survival after initiation of ART. Hazard ratio and Cox proportional-hazard regression model were used to determine predictors of survival time to death. The cumulative probability of survival time at the 6th months after initiation of ART was 96 % and 94 %; 96 % and 96 % for children; adolescents and adults respectively (95 %CI). Mortality was significantly higher among patients with a low initial CD4; advanced WHO clinical disease stage III and IV; INH Prophylaxis; TB infection and bedridden. The present study has shown that there has been low cumulative incidence of mortality for HIV patients. Higher priority should be given to HIV-infected individuals by starting ART therapy during the preliminary stage of their illness.
Keywords: ART, Survival analysis, Cohort, Retrospective, Ethiopia
Edition: Volume 3 Issue 5, May 2014,
Pages: 1462 - 1468