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Research Paper | Pharmaceutical Science | India | Volume 6 Issue 4, April 2017 | Rating: 7 / 10
Development, Validation and Stability Study of UV Spectrophotometric Method for Determination of Tenoxicam in Bulk and Pharmaceutical Dosage Forms
Vilas Karbhari | Warad Tanuja
Abstract: A simple, specific and economic UV spectrophotometric method has been developed using as a solvent 0.1N NaOH Methanol (82) to determine the Tenoxicam in bulk and pharmaceutical dosage formulations. The quantitative determination of the drug has been carried out at a predetermined maxof 370nm, it was proved linear in the range 2-12 g/mL and exhibited good correlation coefficient (R2=0.996) and excellent mean recovery (98-100.09 %). The method was validated statically and by recovery studies for linearity, precision, repeatability and reproducibility as per ICH guideline. The obtained results proved that the method can be employed for the routine analysis of daclatasvirin bulk as well as in the commercial formulations.
Keywords: Tenoxicam, UV Spectroscopy, Validation, Stress Studies
Edition: Volume 6 Issue 4, April 2017,
Pages: 2463 - 2466