Rate the Article: A Prospective Comparative Study between 10ml & 15ml of Normal Saline for Epidural Volume Expansion, with 10mg of 0.5% Intrathecal Hyperbaric Bupivacaine for Elective Surgeries Up to Umbilical Level in Adult Patients, IJSR, Call for Papers, Online Journal
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

Downloads: 100 | Views: 532

Research Paper | Anaesthesiology | India | Volume 9 Issue 1, January 2020 | Rating: 7 / 10


A Prospective Comparative Study between 10ml & 15ml of Normal Saline for Epidural Volume Expansion, with 10mg of 0.5% Intrathecal Hyperbaric Bupivacaine for Elective Surgeries Up to Umbilical Level in Adult Patients

Dr Vinay Kumar Kirla, Dr M. Santhi Sree, Dr B. Sowbhagya Lakshmi


Abstract: INTRODUCTION: The Epidural Volume Expansion (EVE) technique is a modification of CSE, Study is aimed to compare the two Normal saline volumes (NS) (10ml and 15ml) for EVE on spinal anaesthesia with 10 mg of 0.5% hyperbaric bupivacaine for elective surgeries up to umbilical level, with respect to sensory, motor blockade and haemodynamics Methodology: 90 patients of both sexes, aged between 18-60 years, with ASA grade I & 2, are taken and divided into 3 groups, A, B, C (n=30) Group A received 2ml of 0.5% Bupivacaine intrathecally without EVE. Group B received 2ml of 0.5% hyperbaric Bupivacaine and EVE of 10ml NS, and Group C received 2ml of 0.5% hyperbaric Bupivacaine and EVE with 15ml NS. The data obtained was analysed using Cramer's V test, Independent T-test and Anova RESULTS: Maximum level of a sensory blockade is seen in Group C. Time for two-segment regression maximum in Group B, Duration of Anaesthesia is highest in Group B, Duration of Motor Blockade is highest in Group B. Bradycardia, hypotension more in Group C. CONCLUSION: EVE of 10 ml of saline with intrathecal 0.5% Bupivacaine is better compared to EVE of 15 ml of saline with regard to sensory and motor block and hemodynamic stability


Keywords: Epidural, Combined spinal-epidural, Epidural volume expansion


Edition: Volume 9 Issue 1, January 2020,


Pages: 1708 - 1711



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