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Research Paper | Radiology and Medical Imaging Sciences | India | Volume 13 Issue 11, November 2024 | Rating: 4.4 / 10
A Rare Case of Encephalopathy in a 9 Year Old Child
Preethi Senthilkumar, Yogesh Kumar, Priyan Voltaire, J Sai Tarani, Nitishkumar Yeslawath
Abstract: Megalencephalic leukoencephalopathy with subcortical cysts also known as Van Der Knapp disease which is an inherited autosomal recessive disorder with a specific MRI feature and a variable clinical course. On MRI, Frontal and temporal subcortical cysts are the diagnostic hallmark. It usually presents with cerebellar, pyramidal signs and seizures. Megalencephaly can be detected early. It has been seen that it has been more prevalent in north Indian population, however it has been seen globally. We encountered a patient who is a 9 year old male child came with history of developmental delay, seizures with psychotic features. four patients and describe the clinical and radiological features of these patients.
Keywords: megalencephalic leukoencephalopathy, subcortical cysts, Van der Knaap disease, rare encephalopathy, pediatric neurology
Edition: Volume 13 Issue 11, November 2024,
Pages: 1633 - 1634