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Review Papers | Dentistry | India | Volume 13 Issue 8, August 2024 | Rating: 4.8 / 10
Clindamycin in Periodontal Therapy - An Alternative Option?
Abstract: Periodontal disease is an oral infectious and inflammatory disease caused by microorganisms. Antibiotic administration, either systemically or through local delivery, has been shown to improve the clinical outcomes in periodontitis cases after mechanical periodontal treatment. Clindamycin, a lincosamide antibiotic, has shown promise as an alternative treatment in periodontal therapy due to its broad - spectrum activity against Gram - positive and anaerobic bacteria. This review explores the pharmacological properties of clindamycin, its mechanism of action and its potential advantages over traditional antibiotics like amoxicillin and metronidazole. Additionally, the article discusses the use of clindamycin in systemic and local delivery, its efficacy in reducing periodontal disease symptoms and the associated risks of resistance and adverse effects. Overall, clindamycin presents a viable option in the management of periodontal diseases.
Keywords: Antibiotic resistance, Amoxicillin, Metronidazole, Oral biofilm, Periodontitis, Tetracycline
Edition: Volume 13 Issue 8, August 2024,
Pages: 1289 - 1291