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Research Paper | Biochemistry Science | India | Volume 4 Issue 12, December 2015 | Rating: 6.2 / 10
Comparative Evaluation of Salivary Total Proteins in Deciduous and Permanent Dentition
Rahul Deshpande, Suvarna Vinchurkar, Shantanu Deshpande
Abstract: Human saliva plays a vital role in maintaining the integrity of oral tissues. Its composition changes during childhood due to maturation of the salivary glands indicating the need of age-matched controls for the clinical use of saliva as a diagnostic tool for diseases. This study aims at analyzing physiologic variability of naturally occurring total protein concentration in unstimulated whole saliva of children as a function of age. For this study unstimulated whole saliva specimens were collected from 20 healthy children equally divided into Primary (3 - 5 years), Permanent (12 18yrs) dentition age groups. The samples were studied for total protein content by light chromatography coupled with mass spectrometry. The total protein content showed a linear increase with age. Thus this study establishes a correlation between age and salivary composition hence constructing a comprehensive catalogue which forms the basis for salivary total proteins with newer biochemical aids necessary for saliva to serve as a diagnostic aid.
Keywords: Saliva, total proteins, diagnostic tool, deciduous dentition, permanent dentition
Edition: Volume 4 Issue 12, December 2015,
Pages: 528 - 530