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Research Paper | Medical Science | India | Volume 9 Issue 11, November 2020 | Rating: 6.7 / 10
Pneumonia Severity Index and CURB-65 score as a Predictor of In-Hospital Mortality in Acute Exacerbation of COPD
Dr. Pankaj Kumar Singh, Dr. Mohit Bhatnagar, Dr. Sandeep Nimba Deore, Dr. Mandeep Joshi, Dr. Tausif Ahmed, Dr. Subhrojyoti Bhowmick, Dr. Shreya Verma
Abstract: Aim and Objective To investigate the role of Pneumonia Severity Index (PSI) and confusion, Urea, Respiratory Rate, Blood Pressures core (CURB-65) in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disorder with Reference to Mortality Methods In our study a total of 100 patients of COPD with acute exacerbation were included in the study from tertiary care centre, Kolkata for a period of 12 months from December 2015 to November 2016. Results In our study, overall in hospital mortality was 21 %, while mortality in age groups 50-65, 66-80 and >80 were respectively 3.3 %, 28.3 % and 29.41 %. Hence advanced age was associated with significant increase in mortality. The mortality among risk classes of PSI like II, III, IV and V was respectively 0 %, 0 %, 22.22 % and 78.57 % respectively. The percentage of mortality increased significantly as the PSI score increases (p value ≤ 0.001). The mortality associated with the low, intermediate, and high risk classes of CURB-65 was respectively 4.17 %, 14 % and 50 %. Mortality increased with an increase in score demonstrating a significant relation between the two (p value = 0.006). Conclusion Chronic obstructive pulmonary disease (COPD) is a global public health problem and a significant cause of chronic morbidity and mortality worldwide. Infectious are at least 75-80 % of acute COPD exacerbations. Our study detected 21 % in-hospital mortality. A PSI score of >130 i. e. risk class V as well as CURB-65 score of more than equal to 3 i. e. group 3, were strong predictors of in-hospital mortality.
Keywords: Chronic Obstructive Pulmonary Disease, Exacerbation, Mortality, Prognosis
Edition: Volume 9 Issue 11, November 2020,
Pages: 247 - 253