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Research Paper | Pathology | India | Volume 9 Issue 4, April 2020 | Rating: 6.3 / 10
Utility of Immunohistochemical Markers in the Diagnosis of Small Cell Neuroendocrine Carcinoma Cervix - A Case Report
Dr Kalaranjini K V | Dr Sheelavasudevan | Dr Limi Mohandas
Abstract: Neuroendocrine carcinoma (NEC) of cervix is an aggressive histological variant of cervical cancer accounting for about 1-1.5 % of all cervical cancers. High grade ( G3) neuroendocrine carcinoma are highly aggressive tumours and frequently present at an advanced stage. Immunuohistochemical staining for neuroendocrine markers provide support for diagnosis. The 5 year survival for small cell neuroendocrine carcinoma (SCNEC) of all stages reported to be 14-39 % with poorer survival in higher stage disease. The management of high grade neuroendocrine carcinoma may include specific neuroendocrine based systemic chemotherapy and radiotherapy including axial sites.
Keywords: SCNEC, aggressive, immunohistochemistry
Edition: Volume 9 Issue 4, April 2020,
Pages: 1270 - 1272