International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

Downloads: 41 | Views: 277

Informative Article | Periodontology | India | Volume 10 Issue 1, January 2021 | Rating: 6.2 / 10


GCF Biomarkers in Periodontal Diseases

Dr. Maya Mhaske, Dr. Sushma Belkhede, Dr. Mithila Kakade, Dr. Kalyani Reddy


Abstract: The diagnosis of periodontal disease is based on traditional diagnostic parameters such as probing depth, bleeding on probing, clinical attachment levels, assessment of plaque, calculus and alveolar bone levels. These parameters only reflects the past periodontal destruction and not current disease status. Hence various clinical trials have been attempted to identify potential biomarkers of periodontal disease activity. These substances known as biomarkers help in determination of inflammatory mediator levels, as they are good indicators of inflammatory activity. This review highlights recent advances in the use of gingival crevicular fluid (GCF) biomarker-based disease diagnostics that focus on the identification of active periodontal disease.


Keywords: Biomarkers, Saliva, Gingival Crevicular Fluid, Periodontal disease


Edition: Volume 10 Issue 1, January 2021,


Pages: 1325 - 1328



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