Rate the Article: Differences in Initial Lactate Levels on Elderly and Non-Elderly Sepsis Patients Associated With Sofa Score as a Predictor of Mortality in ICU RSUP H. Adam Malik, IJSR, Call for Papers, Online Journal
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

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Research Paper | Medicine | Indonesia | Volume 10 Issue 12, December 2021 | Rating: 5 / 10


Differences in Initial Lactate Levels on Elderly and Non-Elderly Sepsis Patients Associated With Sofa Score as a Predictor of Mortality in ICU RSUP H. Adam Malik

Febrina Sulaiman, Achsanuddin Hanafie, Adi Koesoema Aman


Abstract: Background: Sepsis, a complex syndrome, multifactorial, incidence, morbidity, mortality are increasing. Old age is a predisposing factor due to co-existing comorbidities, repeated hospitalizations, decreased immunity, functional limitations. Hyperlactanemia is a strong independent predictor of death in sepsis. Objective: Know the differences in initial lactate on elderly and non-elderly patients with sepsis associated with the SOFA score as a predictor of mortality. Method: Using a prospective cohort.30 subjects with sepsis who had measured the initial SOFA score, lactate level were taken as samples. The data then analyzed statistically. Results: The difference between the initial lactate of the elderly ? non-elderly was p = 0.724. The difference in the SOFA score was p = 0.089. The difference in initial lactate in dead patients was p = 0.478. The difference in initial lactate in alive was p = 0.226. Significant difference in the initial lactate in elderly patients who died-alive (p = 0.031). Initial lactate was able to predict mortality in elderly patients (p = 0.013). AUC 93.2% (95% CI = 80.2%-100%). Cut-off point (CoP) was 2.1 mmol / L. The initial lactate sensitivity was 81.8%, specificity was 75% in the elderly. Discussion: Women are more than men with severe sepsis had a higher risk of dying in hospital. In elderly, initial lactate of life and death patients, significant differences were found. Conclusion: Initial lactate predicts mortality in the elderly, cut-off point of 2.1 mmol, elderly patients are admitted to the ICU.


Keywords: Baseline lactate level, Sepsis, Age, SOFA score


Edition: Volume 10 Issue 12, December 2021,


Pages: 1333 - 1336



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