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Review Papers | Pathology | India | Volume 13 Issue 1, January 2024 | Rating: 5.3 / 10
Prevalence of Haemoglobinopathies among Different Populations
Remya K. | Sukesh [4]
Abstract: Aim: To establish the prevalence of hemoglobinopathies among different populations. Hemoglobinopathies are the prevalent hereditary illnesses found worldwide. Their frequency varies considerably with geographic location and ethnic group. This paper reviews the literature on the prevalence of hemoglobinopathies among different populations. Design and methods: A systematic literature review to identify peer-reviewed studies on hemoglobinopathies was performed. The inclusion criteria for the search included finding an English-language article published in a peer-reviewed journal that included our keywords and discussed the prevalence of hemoglobinopathies among different populations, including early works pertinent to the current review. For India's tribal communities, sickle cell disease and thalassemia pose serious problems. Of India's total population, the tribal population makes up about 8.5%. As several authors have shown, hemoglobinopathies of various kinds were identified in many Indian tribal communities; sickle cell anemia and beta-thalassemia were the most prevalent illnesses. These illnesses are genetic or hereditary, tend to run in families, and are primarily brought on by consanguineous unions within the tribal society.
Keywords: Hemoglobinopathies, sickle cell anemia, prevalence, tribes, thalassemia, haemoglobin variants
Edition: Volume 13 Issue 1, January 2024,
Pages: 609 - 614