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Research Paper | Medicine | India | Volume 12 Issue 6, June 2023 | Rating: 5 / 10
Red Cell Parameters and their Correlation with Level of Glycemic Control among Patients Undergoing Treatment for Diabetes at a Tertiary Care Centre
Dr. Abhishek .V | Dr. Alvin Treasa George | Dr. Sreeraj [2]
Abstract: Introduction: Diabetes mellitus refers to a group of metabolic disorders that share the phenotype of hyperglycemia. Studies have shown that severity of DM is correlated with the HBA1C level. Red cell parameters are simple and inexpensive parameters used in various workup. Red cell parameters (RDW, MCV, MCHC, MCH) can be considered as a marker of glycemic control in diabetic patients. Aim: To find out whether there is any correlation between Red cell parameters with their glycemic control among patients undergoing treatment for diabetes at a tertiary care centre. Objectives: 1) To find out proportion of patients with deranged Red cell parameters among diabetes patients. 2) To assess the distribution of HBA1C among diabetes patients. 3) To determine whether there is any correlation between Red cell parameters and HBA1C in diabetic patients. Methods: It is a cross - sectional study conducted in Amala institute of medical science for a period of 18 months, that evaluated 250 patients diagnosed with Diabetes Mellitus. These patients had their blood parameters recorded. Data was entered in MS Excel and analyzed using coGuide Statistics software, Version 1. Results: This cross - sectional study was done in 250 diabetic patients, of which 132 were male and 118 were female. Majority of the patients were in the age group of 56 - 75 years. HEMOGRAM and HBA1C levels were compared and a positive correlation was seen between RDW and HBA1C. P value was statistically significant at p<0.001. RDW level increased with increase in HBAIC level. The study indicated that higher the value of HBAIC, higher is the RDW value. Conclusion: RDW along with HBA1C may be considered as a marker of glycaemic control in diabetic individuals as there appears to be a positive correlation between HBAIC and RDW. Erythrocyte indice (RDW) is associated with HbA (1c), independently of plasma glucose levels, in the population. The study highlighted that RDW has a significant correlation with HbA1c and is an inexpensive and freely available test so it may be used as a marker of glycemic status.
Keywords: Red Cell Distribution Width (RDW), HBAIC, RBS
Edition: Volume 12 Issue 6, June 2023,
Pages: 954 - 962