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Research Paper | Medical Microbiology | India | Volume 12 Issue 9, September 2023 | Rating: 4.4 / 10
Antimicrobial Resistance: Unraveling Mechanisms, Impacts, and Novel Intervention Strategies
Saket Gupta, Sagar Gupta, Shivam Agarwal
Abstract: Antimicrobial resistance (AMR) is a pressing global health concern as microorganisms develop resistance to previously effective drugs, endangering public health. Factors like overuse of antibiotics and poor infection control contribute to AMR's rise. Its consequences include prolonged illness, elevated healthcare costs, and reduced treatment effectiveness. Various mechanisms drive AMR, encompassing genetic mutations and horizontal gene transfer. Understanding key terminologies like horizontal gene transfer, selective pressure, and collateral damage is vital. Surveillance tracks resistance patterns, aiding intervention strategies. Technology, including genomic surveillance and point-of-care diagnostics, plays a pivotal role. Novel strategies, such as combination therapy, immunotherapy, and alternative treatments, are emerging. Globally, coordinated efforts, national action plans, and collaboration are needed to combat AMR and safeguard public health.
Keywords: Antimicrobial resistance, Healthcare cost, Encompassing genetic mutations, Horizontal gene transfer, Innervations strategies
Edition: Volume 12 Issue 9, September 2023,
Pages: 1917 - 1922