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Research Paper | Medicine | India | Volume 13 Issue 10, October 2024 | Rating: 4.8 / 10
Factor V Leiden Mutation & Recurrent Venous Thromboembolism: A Rare Case Report
Sakshi Jha, Prashant Udgire
Abstract: Thrombophilia refers to inherited or acquired hemostatic disorders that lead to a predisposition of blood clot formation. Factor V Leiden (FVL), a point mutation of factor V is the most common cause of inherited thrombophilia in a Caucasian population. It is an autosomal genetic disorder, with incomplete penetrance. Therefore, not all individuals who carry this mutation suffer from venous thromboembolism. Here, we report a case of a 20 years old male suffering from recurrent venous thromboembolism in the form of deep venous thrombosis (DVT), with a history of pulmonary embolism & IVC filter in situ.
Keywords: thrombophilia, incomplete penetrance, venous thromboembolism
Edition: Volume 13 Issue 10, October 2024,
Pages: 377 - 378