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Case Studies | Ophthalmology | India | Volume 13 Issue 4, April 2024 | Rating: 4.9 / 10
Posterior Sub - Tenon Injection of Triamcinolone in Non - Resolving Vitreoretinits - A Case Report
Abstract: Study design: Case report. Purpose: To evaluate efficacy of posterior sub - tenon injection of triamcinolone in non - resolving vitreoretinits. Introduction: Vitreoretinits is the inflammation of vitreous and retina. In a non - resolving case of vitreoretinitis steroids are the mainstay of treatment. Steroids can be administered via various routes into the eye. Posterior subtenon injection of Triamcinolone acetonide is an effective treatment option for anatomical and functional improvement in intermediate and posterior uveitis. Methods: A 46 year old female presented to OPD with decreased vision in left eye since 3months. On examination she had BCVA of 6/60 in left eye. Fundoscopy showed vitreous haze grade 3 due to vitritis, multiple vitreoretinal tractional bands extending along both superior and inferior arcade, macular edema and a retinitis patch of less than half disc diameter size just above the superior arcade. Patient was positive for IgG antibodies to CMV and HSV. Patient was started on oral prednisolone 1mg/kgbw OD and topical prednisolone acetate 1.0%, nepafenac 0.3% and timolol 0.5%. Patient was given posterior subtenon injection of 0.5ml of triamcinolone acetonide 40mg/ml. Results: She had 6/12 BCVA at the end of 1month with resolving vitritis and macular edema. By the end of 3months she had with fully resolved vitreoretinitis with 6/6 vision. Discussion: Most steroids used in ophthalmology are glucocorticoids, which have anti - inflammatory and immunosuppressive activity.1 Triamcinolone Acetonide is a minimally water - soluble suspension. Triamcinolone crystals slowly dissolve into the vitreous.3 This creates a diffusional gradient from the vitreous to the macula with minimal systemic exposure. Our study also showed significant improvement in visual acuity and reduction in the macular edema with single posterior subtenon injection of triamcinolone acetonide. Conclusion: A subtenon injection of triamcinolone acetonide appears to be an effective treatment for decreased vision associated with intermediate and posterior uveitis without any significant side effects.
Keywords: uveitis, macular edema, posterior subtenon space, triamcinolone acectonide
Edition: Volume 13 Issue 4, April 2024,
Pages: 476 - 477