Rate the Article: Quantitative Assessment of Pulp Tissue Dissolution after Exposure to 5.25% Sodium Hypochlorite at 1min, 5min, and 60min at 37 ?C and 60 ?C., IJSR, Call for Papers, Online Journal
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

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Experimental Result Paper | Dentistry | India | Volume 13 Issue 5, May 2024 | Rating: 5.2 / 10


Quantitative Assessment of Pulp Tissue Dissolution after Exposure to 5.25% Sodium Hypochlorite at 1min, 5min, and 60min at 37 ?C and 60 ?C.

Dr. Aditi Pande, Dr. Pratima Shenoi, Dr. Mohit Gunwal, Dr. Shriya Shahu, Dr. Gautam Badole, Dr. Rajesh Kubde


Abstract: Context: The success of endodontic treatment mainly depends on effective irrigation methods to dissolve pulpal tissue, remove debris, and clean the complex root canal system. Sodium hypochlorite (NaOCI) is a widely used endodontic irrigant due to its tissue - dissolving and antibacterial properties. Aim: Quantitative evaluation of human pulp tissue dissolution at different temperatures of sodium hypochlorite. Materials and Methods: Twenty - four samples of human pulp tissue were collected from freshly extracted premolars. The samples were divided into two groups: Group I with normal saline and Group II with 5.25% NaOCI. Each group was further divided into two subgroups according to temperature (37?C and 60?C) and three divisions based on time intervals of tissue dissolution (1 minute, 5 minutes, and 60 minutes). Result: The results showed that normal saline did not show any dissolution of pulp tissue. In contrast, 5.25% NaOCl demonstrated a significantly higher tissue dissolution capacity compared to normal saline at both temperatures and all - time intervals. Less pulp dissolution was seen when kept in contact for 1 minute but increased subsequently when kept in contact for 5 minutes to 60 minutes at 60?C. Conclusion: According to the findings of the current study, it can be concluded that 5.25% NaOCl exhibits maximum pulp tissue dissolution at 60?C temperature when kept in contact with pulpal tissue for a minimum of 5 minutes and a maximum of 60 minutes.


Keywords: endodontic irrigation, sodium hypochlorite, pulp tissue dissolution, temperature effects, time intervals


Edition: Volume 13 Issue 5, May 2024,


Pages: 639 - 645



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