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Research Paper | Ophthalmology | Cambodia | Volume 13 Issue 8, August 2024 | Rating: 3.9 / 10
Incidence of and Risk Factors for Steroid-Induced Ocular Hypertension Following Cataract Surgery in 150 Patients Without Glaucoma in Cambodia: A Prospective Study
Virabot SOK [2] | Tithsya HUN | Bunrong SRUN | Channdarith KITH | Kimsreng PRAK [2] | Guechlaing CHEA [2] | Sourn NGETH | Tharith CHAN | Leng UN [2] | Kossama CHUKMOL | Amarin MAR [3] | Sothea AIM | Saly SAINT [3] | Piseth KONG [4]
Abstract: Purpose: This study aims to report the incidence of and risk factors for steroid-induced ocular hypertension in Cambodian patients without glaucoma after cataract surgery. Study Design: A hospital-based prospective observational study. Material and Methods: This study observes the changes in postoperative intraocular pressure in 150 non-glaucomatous patients who underwent phacoemulsification or small manual incision cataract surgeries at Preah Ang Duong Hospital for the incidence of steroid-induced ocular hypertension (defined as intraocular pressure (IOP) higher than 21 mmHg) after using topical prednisolone 1% or dexamethasone 0.1% for 1 month. In addition, risk factors were analyzed. Results: Among 150 patients, 7 patients (4.67%) showed increased intraocular pressure during our study, among whom the younger age group (in their 40s or under), and choice of steroid use (dexamethasone 0.1%) were found to be risk factors. However, all of our steroid-induced ocular hypertension patients had their intraocular pressure notably back to normal (<21 mmHg) after 2 weeks of steroid cessation. Conclusion: This study shows that topical steroid could be safely used by cataract surgeons postoperatively in non-glaucomatous patients with regards to steroid-induced ocular hypertension as the risk is relatively low (4.67%) and the patients? intraocular pressure will return to normal limits upon cessation of steroid. Although some precautions should be taken with patients in their 40s or under and with a choice of steroid, dexamethasone.
Keywords: Cataract, Steroid, Ocular Hypertension
Edition: Volume 13 Issue 8, August 2024,
Pages: 13 - 16