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Review Papers | Biomedical Sciences | Saudi Arabia | Volume 14 Issue 2, February 2025 | Rating: 4.6 / 10
Natural Antioxidants as Promising Radioprotectors: A Mini Review
Ahmed Saleh, Waleed A. Ghaly
Abstract: Radiotherapy is widely used in cancer treatment, but its exposure to ionizing radiation leads to severe side effects due to the generation of free radicals. This review explores the potential of natural antioxidants as radioprotectors to mitigate these effects. Natural antioxidants such as chamomile, Ginkgo biloba, green tea, Angelica archangelica, and ginger exhibit radioprotective properties by scavenging free radicals, modulating inflammatory responses, and regulating apoptosis. Their low toxicity and ability to enhance DNA repair mechanisms make them promising agents in radiation protection. This review highlights the biochemical mechanisms of these antioxidants and their potential clinical applications in radiotherapy.
Keywords: Radiotherapy, ionizing radiation, radioprotectors, natural antioxidants and free radicals
Edition: Volume 14 Issue 2, February 2025,
Pages: 986 - 990