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Research Paper | Chemistry | Nigeria | Volume 4 Issue 9, September 2015 | Rating: 6.7 / 10
Compositional Analysis and Antimycobacterium Tuberculosis Activity of Essential Oil of Hyptis Spicigera Lamiceae Obtained from North-Eastern Nigeria
Runde M. | Kubmarawa D.
Abstract: Fresh leaves of Hyptis spicigera were collected and pretreated for essential oil analysis with the sole aim of linking the ethnomedicinal uses of this plant by the people of Adamawa State Nigeria to its essential oil composition. The results obtained from the analysis shows that 69 compounds were present in varying concentration out of which 18 compounds have appreciable concentration making 80.582 % of the total abundance. The major compound being -Pinene (30.536 %) followed by -Pinene (15.840 %) and Eucalyptol (4.378 %). The essential oil of Hyptis spicigera also showed anti mycobacterium activity when tested on strain 7H9/ADC with MIC of 0.78 %. This activity was compared with standard drug Rifampicin which also has MIC of 0.1 g/ml.
Keywords: Hyptis spicigera, ethnomedicinal, anti-mycobacterium tuberculosis, minimum inhibitory concentration MIC
Edition: Volume 4 Issue 9, September 2015,
Pages: 1040 - 1044