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Research Paper | Biotechnology | India | Volume 6 Issue 12, December 2017
Mutational Study of RAS Subfamily 2CE2 Domain and Fosfestrol as an Ideal Drug Candidate against NSCLC
Jayant Mishra [4] | J. K. Srivastava
Abstract: Lung cancer is a deadly disease that is prevalent as one of the largest contributor to higher mortality rates. Most commonly EGFR is the widely studied factor in almost 90 % of the cases that are considered in the epidemiological study of lung cancer. The present work deals primarily in considering KRAS as an important factor for impending cancer deaths, particularly NSCLC and Designing a potent drug Fosfesterol as a potent target for the same. The basis of the study includes the analysis of a few drug candidates and their activity against NSCLC in comparison to Fosfestrol. Fosfestrol proved to be an effective drug candidate which is ascertained by protein blockage due to correct docking. So fosfestrol may be considered as potent drug against NSCLC for further clinical trials.
Keywords: lung cancer, K-ras, smokers, fosfestrol, NSCLC
Edition: Volume 6 Issue 12, December 2017,
Pages: 1898 - 1901
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Analysis Study Research Paper, Biotechnology, India, Volume 11 Issue 10, October 2022
Pages: 771 - 779Cancer Therapeutics and Delivery Strategies of Bioactive Peptides
Vishnuja Viswanath
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Research Paper, Biotechnology, Indonesia, Volume 11 Issue 12, December 2022
Pages: 1235 - 1239Analysis of Sulforafan Content in Hybrid Broccoli Supplies in MS Media Delivered NAA and BAP and Methionine in Vitro
Wenny Tilaar [5] | Arthur Pinaria | Nelson Nainggolan [6] | Jeany Polii Mandang [2] | Dingse Pandiangan [13]