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Research Paper | Immunology | Iraq | Volume 6 Issue 8, August 2017 | Popularity: 6.6 / 10
The Significance of CXCL10 and CXCL16 in Serum and Placenta of Toxoplasmosis - Induced Abortion
Waheeda Rashid Ali, Ali Hussain Ad hiah, Kawther Abdul Hussian, Mahdi Al-Mussawi
Abstract: The level of CXCL10and CXCL16 was determined in sera and placenta homogenate of toxoplasmosis-induced abortion (25 cases), in addition to 25 cases of accidental abortion. Twenty-five healthy control women were also included for comparison of serum level. CXCL10 level was significantly increased in serum (39.99 ? 1.96 pg/ml) and placenta homogenate (36.35 ? 1.27 pg/ml) of toxoplasmosis-induced\]'\/. , abortion patients, as well as accidental abortion patients (42.27 ? 0.98 and 35.54 ? 1.40 pg/ml, respectively) compared to control serum level (29.66 ? 2.03 pg/ml), while the increases can be more pronounced in serum. For CXCL16 showed a similar pattern of increased level. These results suggest that systemic production of CXCL10, CXCL16 play a significant role in inducing of abortion in toxoplasmosis patients.
Keywords: Toxoplasmosis, Abortion, Chemokines
Edition: Volume 6 Issue 8, August 2017
Pages: 753 - 755
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