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Research Paper | Computer Science & Engineering | India | Volume 3 Issue 6, June 2014 | Popularity: 7 / 10

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Text Studies Classification of Database of Genotypes and Phenotypes using K-Nearest Neighbor Algorithm

Kolekar Suresh S, Kumbhar Satish S

Abstract: The database of genotypes and phenotypes (dbGaP) is the new database to store and distribute data from studies of genome wide association. dbGaP launch by National Library of Medicine (NLM) which is part of National Institutes of Health (NIH). Searching relevant studies of particular interest accurately and completely is challenging task due to keyword based search method of dbGaP Entrez system. For given queries; the dbGaP retrieval system returns several studies that are unrelated; and it is very difficult to find how particular studies are retrieved and why they come out in a particular sequence. Thus; users have to evaluate every study description carefully to find relevant studies; which is time consuming task. Text mining is emerging research field which enable users to extract useful information from text documents and deals with retrieval; classification; clustering and machine learning techniques to classify different text document. In this research; an empirical approach is proposed and implemented with K-nearest neighbor (KNN) machine learning algorithms to classify dbGaP study text in heart; lung and blood studies. It is evident from results that this text based classification outperforms conventional keyword based search of document retrieval system provided by dbGaP.

Keywords: Bioinformatics, Data Mining, Text Mining, database of Genotypes and Phenotypes

Edition: Volume 3 Issue 6, June 2014

Pages: 1146 - 1149

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