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Research Paper | Chemistry | India | Volume 5 Issue 12, December 2016 | Popularity: 6.3 / 10
An Efficient and Simple Procedure for the Synthesis of 4-Substituted Coumarins by von-Pechmann Reaction using Mixture of FeCl3 and Tetrabutylammoniumbromide as Catalyst
Asitanga Ghosh
Abstract: von-Pechmann reaction is modified by using a cheap, easily available and a very effective Lewis acid catalyst - FeCl3. A series of 4-substituted coumarin derivatives have been prepared from a mixture of a phenol derivatives and ethyl acetoacetate using catalytic amount of FeCl3 in nitrobenzene in presence of phase transfer catalyst tetrabutylammoniumbromide
Keywords: von-Pechmann reaction, coumarin, phenol, ethyl acetoacetate and FeCl3 catalyst
Edition: Volume 5 Issue 12, December 2016
Pages: 974 - 976
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