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Research Paper | Pharmaceutical Science | Indonesia | Volume 7 Issue 4, April 2018 | Popularity: 6.9 / 10
Development of Sheet Mask with an Extract Golden Sea Cucumber (Golden Stichoupus V) and Gel Aloe Vera (Aloe vera L.) for Facial Treatment
Rahmatul Qodriah, Swasono R. Tamat, Siti Umrah Noor
Abstract: The extract of golden sea cucumber and aloe vera gel contains collagen and salicylic acid which can be used as anti inflammatory and improve skin moisture. The purpose of this study is to obtain a mask solution containing a combination of golden sea cucumber dust and aloe vera gel that provides anti-inflammatory and moisture effects. Five formulations of mask solution containing 1, 2, 4, 8, 10, % Of sea cucumbers and 5 % aloe vera gel. Mask solution evaluated physical and chemical quality and anti inflammatory test is done by invitro method using Bovine serum albumin (BSA) protein denaturation. Physical stability test was performed for 3 months and volunteer safety test using elimination test, humidity test was performed for 3 hours in the forearm area with parameter of increasing moisture content. The resulting mask solution showed physical stability for 3 months, at a concentration of 8.145mg / mL can inhibit protein denaturation by 50 % (IC50), and provide significantly different moisture compared to blanket solution without sea cucumber
Keywords: Golden sea cucumber Golden stichopus V, aloe gel Aloe vera L, Mask sheet, Antiinflamatory, Corneometer
Edition: Volume 7 Issue 4, April 2018
Pages: 533 - 536
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