Downloads: 164 | Views: 305
Comparative Studies | Medical Science | India | Volume 8 Issue 3, March 2019 | Popularity: 6.7 / 10
Comparison of Two Different Doses of Dexmedetomidine in Decreasing the Extubation Response
Roshni Sebastian, Harshavardhan K
Abstract: BACKGROUND: Laryngoscopy, intubation and extubation is associated with sympathetic stimulation which results in hypertension and tachycardia. Drugs modulating the sympathetic response can be used during extubation to decrease the sympathetic response AIM: To compare of two different doses of dexmedetomidine in decreasing the sympathetic response. . METHOD: A hospital based Prospective, randomized, double blind study where a total of 66 patients undergoing surgery under general Anaesthesia in our hospital were randomly divided into 2 groups: Group-D1: Dexmedetomidine (0.25mcg/kg) group 33 patients; Group-D2: Dexmedetomidine (0.5mcg/kg) group 33 patients. The hemodynamic parameters, airway reflexes were assessed in different intervals of time and compared. RESULT: heart rate and systolic and diastolic blood pressure were significantly lower in D2 group (0.5 g/kg) as compared to D1 group (0.2 g/kg). Smooth extubation was reported in 93.9 % cases of D2 group as compared to 81.8 % in D1 group. Rough experience was seen in 18.2 % cases of D1 group as compared to 6.1 % in D2 group (p-0.25). Mean time for extubation was significantly lower in D2 group (136.7 vs 224.5 sec; p
Keywords: extubation, dexmedetomidine, sympathetic response
Edition: Volume 8 Issue 3, March 2019
Pages: 380 - 383
Make Sure to Disable the Pop-Up Blocker of Web Browser
Similar Articles
Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Research Paper, Medical Science, India, Volume 13 Issue 11, November 2024
Pages: 977 - 981Endotracheal Tube Cuff Pressure Changes in Mechanically Ventilated Patients Undergoing General Anaesthesia with O2, N2o & Other Inhalation Agents in Elective O. T. & in Intensive Care Unit Set-Up with O2 and Air - A Prospective Observational Study
Dr. Nilotpal Das, Dr Mrinal Kanti Taye, Dr. Babita Lahkar, Dr. Putul Pegu
Downloads: 111
Research Paper, Medical Science, India, Volume 8 Issue 12, December 2019
Pages: 984 - 987Epidural Labour Analgesia What's New: Comparison of 0.125% Ropivacaine-Dexmedetomidine versus 0.125% Levobupivacaine-dexmedetomidine
Satinder Kaur, Meena Singh, Arin Choudhury, Pramod Kumar, Namita Misra, Manjit Kaur Mohi
Downloads: 124
Research Paper, Medical Science, India, Volume 9 Issue 1, January 2020
Pages: 1055 - 1060Analgesic Efficacy of Dexmedetomidine Versus Fentanyl as an Adjunct to Thoracic Epidural in Patients Undergoing upper Abdominal Surgery: A Prospective Randomized Controlled Trial
Dr. K. Gopa Naik, Dr. A. Vishnu Vardhan
Downloads: 130
Research Paper, Medical Science, India, Volume 9 Issue 1, January 2020
Pages: 963 - 967Comparison of Dexmedetomidine and Magnesium Sulphate in Attenuating Airway and Hemodynamic Response during Extubation in Patients Undergoing Craniotomies - A Randomised Clinical Trial
Dr Sivanayak Vudithe, Dr. Vindhya K
Downloads: 132
Case Studies, Medical Science, India, Volume 8 Issue 9, September 2019
Pages: 1314 - 1317Effects of Intravenous Dexmedetomidine Premedication on Hemodynamics Changes during Laparoscopic Cholecystectomy
Dr Sweta Gulati, Dr Srinivasa Murthy