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Research Paper | Chemistry | India | Volume 8 Issue 7, July 2019 | Rating: 6.1 / 10
Syntheses, Characterization and Antimicrobial Activity of Triphenyl Antimony (V) Derivatives of Heterocyclic Dithiocarbamate
Deepak Kumar Sharma | Jyoti Sharma [12] | Ramavatar Sharma
Abstract: The reactions of Ph3SbBr2 with the sodium salt of heterocyclic dithiocarbamates in 1: 1 and 1: 2 stoichiometries yield the derivatives and, respectively [Where X = >CH2 (Pipdtc) (1, 6), >CH–CH3 (4-MePipdtc) (2, 7), >O (Morphdtc) (3, 8), >N-CH3 (N-mePzdtc) (4, 9) and >NH (Pzdtc) (5, 10)]. All the newly synthesized compounds have been characterized by elemental analyses, molecular weight measurements and spectral (IR, 1H & 13C NMR and ESI mass) studies. Sodium salt of heterocyclic dithiocarbamates and their corresponding triphenyl antimony (V) bromo- and bis (dithiocarbamate) derivatives have also been screened for their antimicrobial activity against bacteria S. aureus (gram +ve), E. coli, Z. mobilies and P. aeruginosa (gram –ve) and fungi ( P. chrysosprium, A. solani, P. chrysogenum and F. oxisporum).
Keywords: triphenyl antimony V derivatives, heterocyclic dithiocarbamates, antimicrobial activity, spectral studies, anisobidante manner
Edition: Volume 8 Issue 7, July 2019,
Pages: 1601 - 1606