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Research Paper | Medical Science | India | Volume 8 Issue 12, December 2019 | Rating: 6.6 / 10

To Study the Long Term Effects on Corneal Endothelial Cell Density with Mitomycin C Augmented Trabeculectomy Vs Trabecuelectomy without Mitomycin C in Primary Glaucoma: A Comparative Study

Dr. Ankur Kumar ^[4] | Dr. Kishor Kumar ^[4]

Abstract: Purpose: To study the long term effects of Mitomycin C (MMC) assisted trabeculectomy in patients with primary glaucoma on the corneal endothelial cells. Methods: In this study, 60 eyes underwent standard trabeculectomy with mitomycin c (Group I) and 60 eyes of patients underwent standard trabeculectomy without mitomycin c (Group II). Specular microscopy was performed at 1 month, 3 month and 6 month postoperatively. The variable included was corneal endothelial cell density (CECD). Results: Overall, the mean preoperative corneal endothelial cell density was 2572.37 +/-245.82mm2, postoperatively at 1 month, 3 month and 6 month the cell density was significantly reduced to 2388.71 +/- 283.54 mm2, 2332.43 +/- 244.66 mm2 and 2265.53 +/- 238.58 mm2 respectively. (p

Keywords: MMC, Trabeculectomy, CECD

Edition: Volume 8 Issue 12, December 2019,

Pages: 990 - 992