International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 108 | Views: 271 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Case Studies | Paediatrics | India | Volume 9 Issue 1, January 2020 | Popularity: 6.7 / 10


     

Testicular Feminising Syndrome

Jayalakshmi Murupuri, B. Anjaiah


Abstract: Testicular feminization syndrome is a form of pseudo hermaphroditism where phenotypic female has male gonads and is genotypically male. Androgen insensitivity syndrome (AIS), also known as testicular feminization, encompasses a wide range of phenotypes that are caused by numerous different mutations in the androgen receptor gene. AIS is an X-linked recessive disorder that is classified as complete, partial based on the phenotypic presentation. The clinical findings include a female type of external genitalia, 46-XY karyotype, absence of Mullerian structures, presence of Wolffian structures to various degrees, and normal to high testosterone and gonadotropin levels. The syndrome is illustrated by a 15-year-old phenotypic female who presented with a primary amenorrhea, female-type external genitalia, an absent uterus and ovaries, and bilateral testes at the level of the internal inguinal ring. Management includes counseling, gonadectomy (bilateral orchidectomy) to prevent primary malignancy in undescended gonad, and hormone replacement. The karyotyping of family members is advocated because of known familial tendencies.


Keywords: testicular feminising syndrome, orchidectomy,


Edition: Volume 9 Issue 1, January 2020


Pages: 971 - 972



Make Sure to Disable the Pop-Up Blocker of Web Browser




Text copied to Clipboard!
Jayalakshmi Murupuri, B. Anjaiah, "Testicular Feminising Syndrome", International Journal of Science and Research (IJSR), Volume 9 Issue 1, January 2020, pp. 971-972, https://www.ijsr.net/getabstract.php?paperid=ART20204218, DOI: https://www.doi.org/10.21275/ART20204218



Similar Articles

Downloads: 0

Case Studies, Paediatrics, India, Volume 10 Issue 8, August 2021

Pages: 597 - 599

Heiner's Syndrome - A Case Report from Eastern India

Naresh Kumar Shanmugam

Share this Article

Downloads: 0

Case Studies, Paediatrics, India, Volume 10 Issue 11, November 2021

Pages: 474 - 478

Clinical and Radiological Assessment of Children (0-18 Years) with Intracranial Space-Occupying Lesions

Dr. Ghouseya Begam

Share this Article

Downloads: 0

Case Studies, Paediatrics, India, Volume 11 Issue 6, June 2022

Pages: 1646 - 1648

A Case Report on Recurrent Pneumothorax in a Premature Baby

Kannan R., Suganya D., Priya A., Arun Chander K.

Share this Article

Downloads: 0

Research Paper, Paediatrics, India, Volume 11 Issue 9, September 2022

Pages: 410 - 411

Thalassemia Major with Idiopathic Hypertriglyceridemia: A Case Report

Dr. Harsha Bharadwaj Korrapolu, Dr. M. A. Rahman, Dr. Sai Rashmee Ramavath, Dr. Aravya Santosh

Share this Article

Downloads: 0

Case Studies, Paediatrics, India, Volume 11 Issue 10, October 2022

Pages: 1113 - 1113

A Rare Case of Congenital Purpura Fulminans in Neonate

N. V. Ramadevi, Mypati Padmasree

Share this Article
Top