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Case Studies | Medicine | India | Volume 13 Issue 5, May 2024 | Popularity: 5.3 / 10

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Case Report on Nitrofurantoin Induced Peripheral Neuropathy

Dr. Medidhi Adithya, Dr. Bomma Surya Teja, Dr. Saba Kauser, Dr Rana Fatima

Abstract: Background: It is the synthetic antimicrobial and its antibacterial spectrum is broad and is particularly effective against Escherichia coli and Klebsiella and Enterobacter species, hence its use for the treatment of urinary tract infections. Nitrofurantoin neuropathy has a characteristic morphology as demonstrated in the case. Skin biopsy helps to confirm the diagnosis and plays an important role in the management of these patients. Case Report: A 45 Years female patient was admitted with complaints of difficulty in walking, difficulty in eating, difficulty of getting up from squatting position, slurring of speech since 15 days. Discussion: Punch biopsies were performed with a 3 - mm disposable circular punch) after the injection of lidocaine hydrochloride, 2%, under an aseptic technique. The morphology of nerve fibers was observed. Conclusion: Skin biopsy helps to confirm the diagnosis and plays an important role in the management of patients. Nitrofurantoin neuropathy has a characteristics morphology as demonstrated in the case. Skin biopsy helps to confirm the diagnosis and plays an important role in the management.

Keywords: Nitrofurantoin neuropathy, skin biopsy, urinary tract infections, nerve fibers morphology, difficulty in walking

Edition: Volume 13 Issue 5, May 2024

Pages: 680 - 681

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