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Case Studies | Biochemistry | India | Volume 13 Issue 5, May 2024 | Popularity: 5.7 / 10

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Effects of Serum Phosphorus Level among Diabetic Patients of Koshi- Zone: A Study with 0-5yrs. / 5-10 Yrs / 10-15 Yrs / & More than 15 Yrs. Old Diabetic Patients

Dr. Neeraj Kumar

Abstract: Monitoring of Phosphate serum concentration among Diabetic Populations of Koshi Region-Bihar has not been seen in general, probably with a perception that this mineral is sufficiently taken by the public/Patients through their dietary intake and further any mild to moderate hypophosphatemia can be well tolerated & moreover it is strongly believed that the minerals (PO4) is prominently essential for the Bone Mineralization and not that much necessary for its role in Diabetes or its complications management. Whereas the Present study in considerations of its essential role in cells energy productions and its ability to enhance the ability of oxygen to carry more haemoglobin along with its participation in the functions of R.N.A/D.N.A & MITOCHONDRIAL Function and its linked with N.A.D.P/G.T.P & ATP, would be able to proof it that the lack of monitoring of Phosphate level among diabetic Patients would be considered as a Pitfall in the treatment/management of Diabetes Patients and adhering the same may be helpful for the Patients to slower down the Development of Diabetic Complications of any type considering its important role in cells energy productions. There is no any problem to understand it that for the functions of the cells an adequate energy is the utmost requirement & if it is not so we may expect an improper/altered functions of our cells, which finally leads to the development of Diabetic Complications more rapidly, because of the lack of the cellular energy which pull up the conditions of Metabolic Dysfunctions in finality. A correlation of deficiency of Phosphate with age of Diabetes has to be established and expected to be found that the more deficiency would be observed among those Patients, who have more period of time as a diabetic Patient. Keeping the Diurnal Variations in view the time of collections of sample for both Control groups and Group of Diabetic Patients as {0-5 yrs /05-10yrs/ 10-15yrs and more than 15 yrs. Of Diabetic Patients group) would be kept as 3-O?clock in the afternoon on daily basis for Research Purposes, with due consent of patients/public. As a conclusion it has been concluded & strongly presumed that the monitoring of Phosphate level is very- very essential among the Diabetic Patients to prevent themselves from the complications of Diabetes and further make its development (complications of Diabetes) very slower. Aim & Objective of this Study: To make the clinician aware with the data,s of Research- so that accordingly the patients may get benefited in terms of their treatment of either in a condition with Hyper or Hypo- Phosphate along with other complications of Diabetes. Further the reference range for Phosphate I.e 3.4 to 4.5mg/dl has to be re-examined in terms of the local Patient with effect of collection of sample by 3oclock in the afternoon in comparison to control groups.

Keywords: Hypo phosphate/Oxidative-Phosphorylation/Glycolysis/type-1&11 Diabetes/Diurnal changes in phosphate/N.A.D.P-GTP-& ATP2 & ATP-3/Cellular Process & energy

Edition: Volume 13 Issue 5, May 2024

Pages: 798 - 801

DOI: https://www.doi.org/10.21275/ES24511122703

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