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Research Paper | Chemical Pathology | Nigeria | Volume 13 Issue 6, June 2024 | Popularity: 5 / 10
Assessment of Serum Vitamin D in Patients with Hypothyroidism in a Nigerian Tertiary Hospital
Dalili M. S, Hadiru G. M, Dungus M. M, Aisha S. K, Amali A. O, Hassan A. A, Gademi F. M, Fatima M. L, Halima M. A, Musa A. H, Mshelia D. S
Abstract: Introduction: Hypothyroidism is said to be associated with Vitamin D deficiency which is not routinely assessed in hypothyroid patients. The serum level of 1, 25 - dihydroxycholecalciferol and its link to hypothyroidism was assessed. Material and Methods: A total of 70 males and 90 females aged 20 - 60 years were assessed for the study. Evaluation of serum 1, 25 - dihydroxycholecalciferol was done on ELISA monobind Inc. CA 92630, immuno - assay analyzer. Serum fT3, fT4 and TSH were also evaluated by enzyme linked immunosorbent assay (ELISA) technique using stat - fax - 2100. Result: In our study, we have found the values of fT3 in the subjects as 1.21+ 0.89pg/ml lower than controls values of 1.92+0.66pg/ml, values of fT4 in subjects as 0.60+0.53ng/dl as compared to control group value of 1.40+0.30ng/dl, values of TSH as 2.07+1.19miU/L higher than the control group of 0.48+1.67 miU/L. The mean values of 1, 25 - dihydroxycholecalciferol for subjects as 25.80+4.20 nml/L lower than the control group with 35.70+6.30. Conclusion: Our study findings suggest that patients with hypothyroidism also have low serum levels of 1, 25 - dihydroxycholecalciferol (Vitamin D) which can have implications related to numerous organ systems, such as the Bones, Kidneys, Cardiovascular, and Immunological systems.
Keywords: fT3, fT4, TSH, 1, 25 - dihydroxycholecalciferol (Vitamin D), Hypothyroidism and Vitamin D deficiency
Edition: Volume 13 Issue 6, June 2024
Pages: 575 - 578
DOI: https://www.doi.org/10.21275/ES24607081427
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