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Masters Thesis | Medical Surgical | India | Volume 12 Issue 1, January 2023 | Rating: 5.2 / 10

Study on Etiology of Gastroduodenal Perforation in a Tertiary Care Hospital in Northern State of India

Vishal Gautam ^[3] | Sanjeev Gupta ^[3] | U K Chandel ^[2] | Amit Mainra | Ankit Sharma ^[6]

Abstract: Background: Peptic ulcer perforation is a common surgical emergency. The perforation usually involves the first part of duodenum. Early diagnosis and prompt surgical intervention (closure, omentoplasty and toileting) after resuscitation is the key in dealing the threatening perforated peptic ulcer. This study evaluates the prevalence of gastroduodenal perforation in northern state of India. Methods: This is a cross - sectional study conducted at Indira Gandhi Medical College, Shimla on hundred patients who underwent surgery for benign perforated peptic ulcer. Data from 100 patients was retrieved, compiled, summarised and analysed statistically. Result: Hundred patients were included in the study.93% were males and 7% were females. Maximum patients i. e., 28% were in 2nd decade. Male to female ratio of 13.3: 1.76% of the patients were tested positive for H. Pylori Infection and majority of the patients had perforation in duodenum (88%) with low socioeconomic status (79%).32% patients were taking NSAIDs, 75% patients were smokers and 53% patients were used to consume alcohol. Conclusion: Peptic ulcer perforation is common among young males who belongs to low socio - economic status which is due to association of smoking, alcohol intake and H. Pylori infection.

Keywords: Peptic ulcer disease, H. pylori, Gastroduodenal, Perforation, Duodenal ulcer

Edition: Volume 12 Issue 1, January 2023,

Pages: 968 - 971