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Case Studies | Medical Science | Indonesia | Volume 12 Issue 6, June 2023 | Rating: 4.3 / 10
Von Willebr and Disease Type 3 Presenting with Gastrointestinal Bleeding: A Case Report
I Gusti Lanang Rama Dwi Suputra [3]
Abstract: Von Willebrand disease (VWD) causes bleeding due to pro - VWF deficiency. VWD type 3 is the most severe form of this bleeding disease mainly because pro - VWF is nearly completely deficient. It is an inherited autosomal recessive trait, either homozygous or heterozygous gene mutations that affect the blood clotting factors. We present a case of a 25 - years old female diagnosed with VWDtype 3and admitted tothe hospital with complaints of melena. Blood investigations revealed low hemoglobin, and esophagogastroduodenoscopy showed gastritis erosive. This disorder cannot be cured, but the patient must be closely monitored to avoid mortality. Symptomatic treatment can be provided, such as tranexamic acid, desmopressin, factor VWF or VIII concentrate to control bleeding.
Keywords: Von Willebrand disease, VWF, melena
Edition: Volume 12 Issue 6, June 2023,
Pages: 2956 - 2958