International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064




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Informative Article | Medicine | India | Volume 13 Issue 6, June 2024 | Rating: 4.5 / 10


Rare Case of Seronegative Neuromyelitis Optica Presenting with Seizure

Dr. Raj Sachde | Dr Subhashchandra K Gadhvicharan | Dr. Girish Kalsariya


Abstract: Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune condition primarily characterized by optic neuritis and longitudinally extensive transverse myelitis (LETM). Seropositivity for aquaporin-4 antibodies (AQP4-IgG) has been considered a hallmark of NMOSD. However, this case presentation focuses on an exceptional case of NMOSD in a 28 year old female presenting with 1st episode of seizure who didn?t exhibit evidence of AQP4-IgG seropositivity. Keywords ? Seronegative Neuromyelitis Optica ? Generalized Tonic-Clonic Seizures.


Keywords: Seronegative Neuromyelitis Optica, Generalized Tonic-Clonic Seizures, Atypical NMO Presentation, AQP4-IgG Negative, Autoimmune Neurological Disorder


Edition: Volume 13 Issue 6, June 2024,


Pages: 1814 - 1815



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