International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Case Studies | Dermatology | India | Volume 14 Issue 1, January 2025 | Popularity: 4.3 / 10


     

A Clinical Evaluation of Serum Vitamin D Levels in Patients with Vitiligo

Dr. Prathyusha Prabhakar


Abstract: Background: The autoimmune hypothesis highlights the potential role of low serum vitamin D levels in the pathogenesis of vitiligo. This study aimed to determine the association between serum vitamin D levels and vitiligo. Fifty adult vitiligo patients and fifty healthy controls were included in this case - control study. Serum vitamin D levels were measured and analyzed statistically. The findings revealed significantly lower serum vitamin D levels in vitiligo patients, with variations observed based on disease severity and extent. Results: There was a significant difference in mean vitamin D3 levels among vitiligo patients with localized, generalized, and universal disease involvement (p < 0.001). These results suggest that vitamin D deficiency may play a role in vitiligo progression, emphasizing its potential as a therapeutic target.


Keywords: Vitamin D3, vitiligo, melanocytes, autoimmune disorders, dermatology


Edition: Volume 14 Issue 1, January 2025


Pages: 449 - 452


DOI: https://www.doi.org/10.21275/MR25110094339



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Dr. Prathyusha Prabhakar, "A Clinical Evaluation of Serum Vitamin D Levels in Patients with Vitiligo", International Journal of Science and Research (IJSR), Volume 14 Issue 1, January 2025, pp. 449-452, https://www.ijsr.net/getabstract.php?paperid=MR25110094339, DOI: https://www.doi.org/10.21275/MR25110094339