International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Chemistry | India | Volume 5 Issue 1, January 2016 | Popularity: 6.3 / 10


     

A Novel Approach to the Synthesis of Some Naphthofuran Derivatives Bearing Polar Substituents for Studying their Antimicrobial Activity

Dr. Amar Singh Yadav, Kaman Singh


Abstract: -Naphthol on reaction with N- (hydroxyalkyl) -arylamides/ imides (1) in ethanol containing catalytic amount of conc. HCl furnishes N- (2-hydroxy-naphthalen-1-yl-alkyl) -arylamides/ imides (2) which on treatment with benzoin in dioxan containing triethylamine (TEA) affords N- (2, 3- diphenyl-naphtho [2, 3-b] furan-9-yl-alkyl) - arylamides/ imides (3). Compounds 3 have been evaluated for their antimicrobial activity involving four bacterial and six fungal strains.


Keywords: Antimicrobial resistance, nitrofurazone, amidoalkylation


Edition: Volume 5 Issue 1, January 2016


Pages: 606 - 608



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Dr. Amar Singh Yadav, Kaman Singh, "A Novel Approach to the Synthesis of Some Naphthofuran Derivatives Bearing Polar Substituents for Studying their Antimicrobial Activity", International Journal of Science and Research (IJSR), Volume 5 Issue 1, January 2016, pp. 606-608, URL: https://www.ijsr.net/getabstract.php?paperid=NOV152767, DOI: https://www.doi.org/10.21275/NOV152767



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Chemistry, Nigeria, Volume 7 Issue 12, December 2018

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A Review of Methods Used for Seed Oil Extraction

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