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Research Paper | Pathology | India | Volume 12 Issue 6, June 2023 | Rating: 5 / 10
HPV Infection in Cervicalbiopsy and Hysterectomy Specimens of Reproductive Age Females - A Hospital Based Prospective Study
Jignesh Kumar M. Dangi | Seema Baxi [2]
Abstract: Introduction: Human papilloma virus (HPV) is most common cause for cervical cancer all over world. A study from Mumbai has shown the prevalence of HPV to be 25% in CIN-I &up to 66% in CIN II .There is no data and research about the relation of HPV infection with cervical cancer in the Gujarat region including Bhavnagar district. Aims and objectives: 1. To assess prevalence of HPV infection in cervical biopsy and hysterectomy specimens of women of reproductive age group at Sir T Hospital, Bhavnagar. 2. To assess association of HPV with cervical dysplasia and/or cancer. Materials & methods: A prospective hospital based study of HPV by IHC was done on all cervical tissues and hysterectomy specimens. Inclusion Criteria: All cervical biopsy & hysterectomy specimens of reproductive age females. Exclusion Criteria: 1. Cervix assessed by PAP Smear2. Autolysed samples. Result: 37.5% of hysterectomy specimens and 4.2% of cervical biopsies were positive for HPV. The maximum number of patients & HPV positivity was seen in the 4th decade. Conclusion: The proportion of HPV infection in cervix of females in Bhavnagar was 41%.
Keywords: Cervical cancer, HPV, Koilocytes
Edition: Volume 12 Issue 6, June 2023,
Pages: 1374 - 1376