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Research Paper | Microbiology | India | Volume 9 Issue 3, March 2020 | Rating: 6.9 / 10

Prevalence of Helicobacter Pylori Infection among Adults undergoing Gastrointestinal Endoscopy

Dr. Chandramohan Yadav | Dr. Rohini Suryawanshi | Dr. Rhema Suryawanshi

Abstract: Aim: To determine the prevalence of H. pylori infection in adults undergoing oesphagogastrodudenoscopy by two different methods, serology (ELISA technique) comparing it with histopathology. Material and Methods: Forty patients attending surgery OPD of a tertiary care hospital for GI endoscopy were involved in this study. Their biopsies and sera were sent to Histopathology and Microbiology department respectively for detection of Helicobacter pylori. Results: H. pylori Ab (IgG) was detected in the sera of 25 (63 %) patients by ELISA, 15 (37.50 %) of them showed H. pylori in their biopsies also by Giemsa stain. Most patients with detectable antibodies to H. pylori were those with chronic gastritis; however patients complaining from reflux oesophagitis showed significant absentee of this Ab. Conclusion: In view of the better results obtained for invasive vs non-invasive test, for a more accurate diagnosis, it is advisable not to solely rely on non-invasive methods of Helicobacter pylori diagnosis.

Keywords: Endoscopy, ELISA, Helicobacter pylori

Edition: Volume 9 Issue 3, March 2020,

Pages: 576 - 578