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Research Paper | Pharmacy | India | Volume 10 Issue 2, February 2021 | Popularity: 6.7 / 10

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Purification, Characterization and Evaluation of Babool Gum as Pharmaceutical Excipients

Vandana Chaudhary, Ravi Kumar Patel, Rishabha Malviya

Abstract: Natural polymers have been widely used pharmaceutical formulations. In present investigation Gum was purified from crude babool gum (Acacia nilotica) and further characterized to be used as a pharmaceutical excipient. A water based isolation and purification and characterization of babool gum was done. Characterization was based on various parameters such as test for carbohydrates, test for purity, organoleptic properties, ash value, solubility behavior, pH, swelling index, surface tension, viscosity, particle size, bulk density, tapped density, bulkiness, powder flow behavior, etc. Results showed that polymer is white in colour with pH 6.8. Bulk density, tapped density, carr’s index and angle of repose were found to be 0.631±0.01 (cm3/g), 0.91±0.01 (g/cm3), 30.51 ( %), 74±0.74 (°) respectively. The isolated polymer can be used as a pharmaceutical excipient in different pharmaceutical dosages forms.

Keywords: Pharmaceutical excipients, babool gum, Binding agent, Natural polymer, mucoadhesive

Edition: Volume 10 Issue 2, February 2021

Pages: 1205 - 1209

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