International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 1 | Views: 199

Research Paper | Pharmacy | India | Volume 10 Issue 6, June 2021 | Popularity: 4.6 / 10


     

Simultaneous Estimation of Amprolium Hydrochloride and Sulfaquinoxalin using Simultaneous Equation Method

Sruthi .K, Prasanth .S .S, Preethi .P .R, Athulya .K .K, Panchami .G .S


Abstract: The objective of the study is to develop simple, precise, authentic and cost effective analytical method for the estimation of antiprotozoal drugs. Accurate and precise analytical methods were developed for the analysis of amprolium hydrochloride and sulfaquinoxalin sodium in bulk and formulation. The drugs are antiprotozoal drugs which are active against Coccidiosis. 234 nm and 248 are the ?max or the absorption maximum of Amprolium hydrochloride and Sulfaquinoxalin sodium respectively. The isobestic point was 242 nm. The UV methods are developed by using 2-10?g/ml of AMP. Hcl and 1.5- 7.5?g/ml SQS. In simultaneous equation method correlation coefficient of AMP. Hcl was 0.99928.Sulfaquinoxalin shows correlation coefficient of 0.99780. Developed methods are validated as per ICH guidelines.


Keywords: Amprolium hydrochloride, sulfaquinoxalin, antiprotozoal, method validation


Edition: Volume 10 Issue 6, June 2021


Pages: 682 - 688



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Sruthi .K, Prasanth .S .S, Preethi .P .R, Athulya .K .K, Panchami .G .S, "Simultaneous Estimation of Amprolium Hydrochloride and Sulfaquinoxalin using Simultaneous Equation Method", International Journal of Science and Research (IJSR), Volume 10 Issue 6, June 2021, pp. 682-688, https://www.ijsr.net/getabstract.php?paperid=SR21607130845, DOI: https://www.doi.org/10.21275/SR21607130845