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Review Papers | Pharmaceutical Science | India | Volume 10 Issue 9, September 2021 | Popularity: 5 / 10

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A Review on "Pilot Plant Scale - Up Techniques for Tablet"

Vinod. K. Bhendale, Ganesh. V. Dhakne

Abstract: Pilot plant scale up techniques it is the part of pharmaceutical industry where a lab scale formula is transformed in to large scale by development of liable and practical procedure of manufacturing. Pilot plant scale up techniques for solid dosage form will provide guideline for manufacturing to large scale process and these will play crucial role in large scale manufacturing. General requirement for scale up such as reporting responsibility, personnel requirement, space requirement, review of formula, raw material, processing equipments, production rate, gmp consideration and the parameters such as blending, granulation, drying, compression will provide critical role in development of solid dosaseform. Pilot plants are relatively smaller than full scale production plant. Also a pilot plant intended for learning, the preparation of several clinical batches in the pilot plants provides its personnel with the opportunity to perfect and validate the process.

Keywords: Pilot Plant, scale Up Techniques, Solid Dosage Form, Tablet, Drying, Blending, Compression

Edition: Volume 10 Issue 9, September 2021

Pages: 875 - 881

DOI: https://www.doi.org/10.21275/SR21909120436

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