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Research Paper | Medical Science | Albania | Volume 11 Issue 11, November 2022 | Popularity: 4.1 / 10

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Immunohistochemical Markers of Endometrial Carcinoma

Armela Priftaj, Esmeralda Thoma

Abstract: Endometrial carcinoma (EC) is the most common gynaecologic malignancy among women worldwide with 287, 000 new casesand 74, 000 mortalities per year. EC is the fourth most common type of cancer in females. Traditionally, ECs have been classified into two types. The more common is type I, mostly endometrioid carcinomas, which are estrogen - dependent cancers with a relatively good prognosis. On the other hand, type II tumours are not estrogen - driven and affect older age groups. These tumours have a poor prognosis and demonstrate more common extrauterine spread. The prototype for this group is serous carcinoma. In order to improve the efficacy of EC treatment, identification of high - risk prognostic factors is a high research priority. Early assessment could enable conservative therapy in patients with favorable prognosis as well as reserve effective and more radical therapy for patients with aggressive forms of the tumor.

Keywords: endometrial carcinoma, immunohistochemical markers

Edition: Volume 11 Issue 11, November 2022

Pages: 591 - 594

DOI: https://www.doi.org/10.21275/SR221107234515

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