Downloads: 1 | Views: 215 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Comparative Studies | Orthopedic | India | Volume 11 Issue 12, December 2022 | Popularity: 4.6 / 10

Rate This Article!      

A Comparative Study on Management of Pain in Patients with Osteoarthritis Receiving Monotherapy of Piroxicam Verses Piroxicam in Combination with Duloxetine

Sara Shreen, Mazharuddinali Khan, Hafsafirdose, Mohammad Yousuf Younus, Syeda Fatima Begum, Syed Majid

Abstract: Osteoarthritis is the most common bone disorder accounting for the majority of long - term disabilities as it usually affects weight - bearing joints such as the cervical, lumbosacral spine, knees, hips, as well as feet. A six - month observational study was conducted in orthopedic outpatient department. Demographic data and other pertinent information were collected. The data was assessed using WOMACS and NPR scale. Group 1 received piroxicam, and group 2 received piroxicam and duloxetine. The mean of patients in Group 1 was (55.16?11.20) and in Group 2 was (58.22?10.62). In comparison of both groups Males (62%) were dominant in group 1 whereas in Group 2 females were dominant (56). The mean height of patients in Group 1 was 5.5?2.00 and in Group 2 was 5.3?1.90. The mean weight of patients in Group 1 was 67.75?11.02 and in Group 2 was 64.2?11.84. Data were assessed using an unpaired t - test. The WOMAC score, NRS rating, and CRP levels of Group B were significantly lower than Group A. When monotherapy with piroxicam fails combination therapy can be used instead of switching to opioids.

Keywords: Comparative, OA, Pain, Piroxicam, Duloxetine

Edition: Volume 11 Issue 12, December 2022

Pages: 840 - 845

DOI: https://www.doi.org/10.21275/SR221213153945

Make Sure to Disable the Pop-Up Blocker of Web Browser

Click to Cite this Article

Similar Articles