Downloads: 3 | Views: 165 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Research Paper | Anaesthesiology | India | Volume 12 Issue 1, January 2023 | Popularity: 5.1 / 10
Paediatric Spinal Anaesthesia - With and Without Clonidine as adjuvant
Flory Judy Britto, Prasad K Kulkarni
Abstract: Introduction: This study was done to compare the efficacy and safety of spinal anaesthesia, duration and quality of post operative analgesia using intrathecal bupivacaine alone and bupivacaine plus clonidine. Objective: A prospective randomised single blinded study was carried out in 60 ASA - 1 paediatrics patients between the age group of 1year to 18 years undergoing surgeries below T8 dermatome up to 2 hrs duration. Patients were randomly allocated in two groups. Method: Group - A received 0.5% bupivacaine heavy (0.4mg/kg for 5 - 15kg or 0.3mg/kg for >15 kg) and Group - B received bupivacaine 0.5%heavy (0.4mg/kg for 5 - 15kg or 0.3mg/kg for >15kg) and preservative free clonidine (1 mcg/kg), comprising 30 patients each. Time of onset of sensory block, maximum level of sensory block, duration of sensory block, duration of post - op analgesia was observed. Results: Mean duration of sensory blockade (147.68?7.28 vs 260.33?9.03min; P<0.001) and motor blockade (132.5?10.06 vs 233.33?8.58min; P < 0.001) and duration of analgesia (172?10.61 vs 324.50?26.55min; P < 0.001) were significantly prolonged in the clonidine group. In the control group, most patients needed three analgesic doses over 24hr while in the clonidine group, the majority needed two doses. Adverse effects were infrequent in both groups. Conclusions: Clonidine as an adjuvant to 0.5% bupivacaine heavy significantly prolonged the duration of analgesia with improved quality of anaesthesia while maintaining safety. We recommend the routine use of clonidine 1 ?g/kg dose as an adjuvant to 0.5% bupivacaine in paediatric Spinal Anaesthesia.
Keywords: Paediatric anaesthesia, clonidine. Bupivacaine, spinal anaesthesia, analgesia, pre - medication, adjuvant
Edition: Volume 12 Issue 1, January 2023
Pages: 102 - 104
DOI: https://www.doi.org/10.21275/SR221230200821
Make Sure to Disable the Pop-Up Blocker of Web Browser
Similar Articles
Downloads: 0
Case Studies, Anaesthesiology, India, Volume 10 Issue 12, December 2021
Pages: 105 - 106Case Report on Tracheo - Oesophageal Fistula in a New Born - An Anaesthetist's Challenge
Dr. Aradhana Devi, Dr. Olvyna D'souza
Downloads: 0
Research Paper, Anaesthesiology, India, Volume 11 Issue 5, May 2022
Pages: 1191 - 1195Comparative Study of Intravenous Fentanyl Vs Nebulisation Fentanyl for Postoperative Analgesia in Patients Undergoing Lower Limb Surgeries - A Randomised Controlled Study
Dr. Thillai Arasu, Dr. Pradeep Charan, Dr. Arun Satish, Dr. S. P. Chittora
Downloads: 0
Comparative Studies, Anaesthesiology, India, Volume 11 Issue 11, November 2022
Pages: 414 - 416Dexmedetomidine as an Adjuvant to Levobupivacaine in Paravertebral Block for Postoperative Analgesia after Breast Cancer Surgery
Dr. Mudhanuru Bhargava Mallesh Yadav, Dr. G. Vijaya Lakshmi, Dr. Anil Kumari, Dr. Joga Aparna
Downloads: 0
Masters Thesis, Anaesthesiology, India, Volume 11 Issue 11, November 2022
Pages: 542 - 546Comparison of Efficacy of Pre-Operative Oral Pregabalin versus Oral Gabapentin on Postoperative Analgesia in Patients undergoing Lower Abdominal Surgeries under Spinal Anaesthesia : A Prospective, Randomized, Controlled Study
K. K. Arora, Ritu Pauranik, Malathi Bhaskar
Downloads: 1
Masters Thesis, Anaesthesiology, India, Volume 10 Issue 6, June 2021
Pages: 568 - 569A Study Comparing the Efficacy of Postoperative Analgesia with Fascia-Iliaca Compartmental Block vs IV Tramadol In Surgeries Around Hip
Dr. Firdous Fatima, Dr M. H. Nagrale