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Research Paper | Medicine | Qatar | Volume 11 Issue 4, April 2022 | Popularity: 5.4 / 10

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Diabetic Dyslipidaemia: The Association between Diabetes Mellitus and Deviations of Lipid Metabolism

Nesrin Shiekh Sulyman, Fatima Ibrahim Mohamed Abdulla

Abstract: One of the most serious macrovascular consequences of diabetes mellitus is diabetic dyslipidaemia. Diabetic dyslipidaemia has a prevalence and incidence that is similar to diabetes mellitus. Aim of the current study was to investigate the association between diabetes mellitus and deviations of lipid metabolism, the study also explored the numerous challenges that treat diabetic dyslipidaemia. Methodology: The current study was searched using a variety of key words such as "Diabetes mellitus and/or Dyslipidaemia" "Dyslipidaemia and/or Insulin resistance", "Dyslipidaemia and/or Type 2 diabetes" and "Type 2 diabetes and/or complications", "Dyslipidaemia and/or complications", "Diabetic dyslipidaemia and/or obesity", "Obesity and/or complications", "Diabetes mellitus and/or Hyperlipoproteinemia". Those articles were derived from the data related to diabetes mellitus and/or dyslipidaemia and reported cases were conducted utilizing seven electronic databases (CINAHL, MEDLINE, ProQuest, PubMed, Scopus, Science Direct, and Cochrane) for studies published in various languages from January 2021 to May 2021. According to the findings, diabetic dyslipidaemia is a common illness in which insulin resistance is thought to be the main force behind the lipid abnormalities. Hypertriglyceridemia, low HDL cholesterol, and high small dense LDL levels are all related physiologically, with hypertriglyceridemia being the most prominent trait. Diabetic dyslipidaemia can be effectively managed to reduce the risk of CVD. The most essential treatment techniques are lifestyle and pharmaceutical therapies. The most effective way to reduce cardiovascular risk in diabetes patients is to take statins on a regular basis. In the search for new therapeutic strategies, it's critical to improve our understanding of the pathophysiology of lipid abnormalities in diabetic patients and to expand our knowledge of existing lipid-lowering drugs so that their role in the management of diabetic dyslipidaemia can be clearly defined. The study emphasizes the detrimental consequences of dyslipidaemia.

Keywords: Dyslipidaemia; Insulin resistance; Type 2 diabetes; Diabetic dyslipidaemia; Hyperlipoproteinemia type II

Edition: Volume 11 Issue 4, April 2022

Pages: 1055 - 1065

DOI: https://www.doi.org/10.21275/SR22419144427

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