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Research Paper | Natural Science | Malaysia | Volume 12 Issue 10, October 2023 | Rating: 4.9 / 10
Comparative Study on the Phytochemical Screening and Antioxidant Activity of Melastoma Malabathricum and Gynura Procumbens Extracts
Abstract: Malaysia is blessed to have a variety of natural resources of plants that are given beneficial for human well-being. Plants are a rich source of natural phytochemical compounds such as secondary metabolites and antioxidant. Phenolic compounds are the richest secondary metabolites commonly found in both edible and non-edible plant. Antioxidants play an important role to protect damage caused by oxidation process. The present study was designed to determine the antioxidant activities of aqueous leaves extract of Melastomamalabathricum (senduduk) and Gynurap procumbens (sambungnyawa). M. malabathricum usually used to treat diarrhoea, dysentery, hemorrhoids, cuts and wounds, toothache, and stomachache. Traditionally, G. procumbens commonly used in several countries to treat a wide range of health conditions, including kidney discomfort, arthritis, diabetes, constipation, and hypertension. In this study, the sample was extracted using aqueous extraction. Next, the phytochemical screening test was done to determine the presence of tannin, terpenoids, steroid, phenolic, flavonoids and saponin content. The antioxidant activities in this study were determined by total antioxidant capacity, DPPH (1,1-diphenyl-2-picrylhydrazine) radical scavenging assay. From the phytochemical screening test of aqueous extraction of M. malabathricum showed the presence of phenolic, flavonoid, tannin, steroid but absence of saponin, tannin and steroid. Whereas, G. procumbens screening, it shows presence of all phytochemical but absent of saponin. The antioxidant activity expressed as IC50 ranged from 0.31mg/ml for G. procumbens and 0.42 mg/ml for M. malabathricum. The potency of radical scavenging effect of G. procumbens extract was greater than M. malabathricum. Further study is needed to identify and isolate the exact active compound underlying this high antioxidant activity.
Keywords: Phenolic compounds, Antioxidant, DPPH, IC50
Edition: Volume 12 Issue 10, October 2023,
Pages: 1268 - 1271