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Research Paper | Obstetrics and Gynecology | India | Volume 12 Issue 11, November 2023 | Rating: 5.2 / 10
FETO - Maternal Outcome in Pregnant Women with Hemoglobin E Trait in a Tertiary Care Hospital: An Observational Study
Dr. Rajlakhi Khattiya Deori | Dr. Ramesh Sonowal [2] | Dr. Farzana Zahir | Dr. P. M Vandhana
Abstract: Introduction: The NE India and the state of Assam in particular has a very high prevalence of HbE trait. The incidence of HbE in the Bodo Kachari population of Assam has been reported to be 64.5%, the highest observed frequency of this mutation in the world. Objective: To assess the pregnancy outcome among women with HbE trait. Methods and Materials: A hospital based prospective longitudinal study was conducted in a tertiary care hospital for a period of 1 year to identify singleton pregnant women with HbE trait by High performance liquid chromatography and to study their pregnancy outcome. Study was observed on the maternal variables of gravida , mode of delivery , sepsis , degree of anemia, Antepartum hemmorhage , postpartum haemmorhage, asymptomatic bacteriuria ,prolonged hospitalisation, shock, need for blood transfusion, maternal death. Fetalvariables were IUFD, FGR, LBW, abortion, neonatal death, jaundice, birth asphyxia, preterm, NICU admissions, macrosomia and the need for phototherapy. Result: During the study period, 190 pregnant women with HbE trait were included and were followed up till delivery. Hundred percentage of participants were found to be anemic. Most of them were mildly anemic. Fifty percent subjects were primigravida. There was1.05 % abortions, 15.2 % preterm births, 5.7 % Fetal growth restriction, 14.2% Low birth weight. 12.1 % needed NICU admission, Neonatal jaundice was present in 10.5%. 3.3 % neonatal death were observed. Conclusion: There were no serious adverse maternal outcomes. Whereas fetal outcomes showed a significant number of preterm births,fetal growth restrictions, low birth weight, neonatal jaundice and neonatal intensive care .
Keywords: haemoglobinopathy, HbE, anemia in pregnancy, northeast India
Edition: Volume 12 Issue 11, November 2023,
Pages: 344 - 347