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Case Studies | Toxicology Science | India | Volume 12 Issue 12, December 2023 | Popularity: 5 / 10
Effect of Haemodialysis in Phenobarbital Toxicity: A Case Report
Dr. Azharuddin Patel, Dr. Tilottama Parate, Dr. Nitin Bhure, Dr. Sandeep Charde
Abstract: A 18 years old male presented with coma caused by a phenobarbital toxicity, requiring critical care admission. This male has done suicide attempt by consuming multiple tablets of Phenobarbitone of 60mg each around 50 tablets (total 3 gm). Phenobarbital is a long-acting barbiturate, which in an overdose can cause central nervous system depression, respiratory failure and haemodynamic instability; these patients can remain obtunded for many days. After initial supportive therapy, he was dialysed to help in elimination of the drug. Haemodialysis resulted in markedly reduced plasma level of phenobarbital, which decreased the length of stay in critical unit and aided full recovery.
Keywords: coma, phenobarbital toxicity, suicide attempt, overdose, haemodialysis
Edition: Volume 12 Issue 12, December 2023
Pages: 791 - 792
DOI: https://www.doi.org/10.21275/SR231207222036
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Toxicology Science, Indonesia, Volume 8 Issue 7, July 2019
Pages: 132 - 137Toxicity of Industrial Palm Oil Waste Water and Sub-Lethal Test to Oreochromis sp.
Syafriadiman
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Toxicology Science, Kenya, Volume 8 Issue 5, May 2019
Pages: 434 - 439Biodegradation of Applied Plant Extracts of C. cinerariifolium, E. camaldulensis and N. tabaccum in the Habitats of Third Instar Larvae of the Malaria Vector Anopheles gambiae s.s. Giles (Diptera: Culicidae) Larvae is a Function of Time
Glenn O. Araka
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Toxicology Science, Kenya, Volume 8 Issue 5, May 2019
Pages: 381 - 388The field Strain of Anopheles gambiae s.s. Giles Larvae Resistance Ratio (RR) is Twice That of Susceptible (Laboratory Reared) Strain when Tested with Plant Crude Flower and Leaf Extracts
Glenn O. Araka
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Toxicology Science, Kenya, Volume 8 Issue 5, May 2019
Pages: 393 - 400Synergistic Combinations of Flower and Leaf Extract Activities of C. cinerariifolium , E. camaldulensis and N. tabaccum Outweigh the Activities of Antagonistic Combinations
Glenn O. Araka
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Toxicology Science, India, Volume 5 Issue 6, June 2016
Pages: 356 - 361Hydrogen Sulphide Exposure on Lipid Peroxidation and Antioxidant Enzymes in Fishes
Sreejai R., Chithra V. S.