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Research Paper | Gynaecology | India | Volume 12 Issue 12, December 2023 | Rating: 5.4 / 10
Endometrial Compaction and its Impact on IVF Outcomes
Dr. M. Sree Supriya [2] | Dr. K. M. Kundavi | Dr. Geetha V [4] | Dr. Rashmi G V | Dr. Nithya M Naaram [3]
Abstract: Purpose: To study the IVF outcomes in women having endometrial compaction undergoing frozen embryo transfer cycles. Methods : It is a prospective observational study involving eighty women undergoing frozen embryo transfer(FER) at the Institute of Reproductive Medicine and Women?s health, Madras Medical Mission, Chennai, a single academically affliated fertility centre. Endometrial preparation for these cycles started on Day 2 after a baseline transvaginal scan. Endometrial thickness is measured on the day of starting progesterone and endometrial compaction is checked on the day of embryo transfer by transvaginal scan. Once frozen embryo transfer is done, patients are started on full luteal support and advised to confirm pregnancy by a serum beta hCG after 2 weeks. If positive, a transvaginal scan is done 2 weeks later to confirm a pregnancy. Results: Only 30 % (24/80) of the cycles demonstrated compaction whereas 70 % (56/80) either expanded or remained unchanged. Overall clinical pregnancy rate was 38.75 %. There were no differences in the patient?s age, body mass index, cause and duration of infertility, parity, baseline Follicle stimulating hormone, Anti-Mullerian hormone, or day of transfer between the groups. When comparing cycles with and without compaction, no significant difference was seen in pregnancy rate. Conclusion: This study investigates the relationship between endometrial compaction and the success rates of IVF treatments. Despite the observed variations in endometrial compaction, our findings indicate no significant correlation with pregnancy outcomes. These results contribute to the understanding of factors influencing IVF success and suggest the need for further research in this area.
Keywords: Endometrial compaction; Progesterone; Frozen embryo transfer; Pregnancy rate
Edition: Volume 12 Issue 12, December 2023,
Pages: 1710 - 1714